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首页>>免疫学>>一抗>>前列腺肿瘤高表达蛋白1抗体
前列腺肿瘤高表达蛋白1抗体
  • 产品货号：
    BN40236R
  • 中文名称：
    前列腺肿瘤高表达蛋白1抗体
  • 英文名称：
    Rabbit anti-PTOV1 Polyclonal antibody
  • 品牌：
    Biorigin

  • 货号

    产品规格

    售价

    备注

  • BN40236R-100ul

    100ul

    ¥2120.00

    交叉反应（总）:Human,Mouse,Rat,;推荐应用:IHC-P,

  • BN40236R-200ul

    200ul

    ¥3140.00

    交叉反应（总）:Human,Mouse,Rat,;推荐应用:IHC-P,

产品描述

英文名称PTOV1
中文名称前列腺肿瘤高表达蛋白1抗体
别    名ACID2; Activator interaction domain containing protein 2; Gcap3; prostate tumor overexpressed 1; Prostate tumor overexpressed gene 1; PTOV 1; PTOV1_HUMAN; Prostate tumor-overexpressed gene 1 protein; PTOV-1; Activator interaction domain-containing protein 2.  



研究领域肿瘤  免疫学  染色质和核信号  转录调节因子  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, 
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量47kDa
细胞定位细胞核 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human PTOV1:61-160/416 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed
产品介绍PTOV1 belongs to the Mediator complex subunit 25 family, PTOV1 subfamily. It may activate transcription and is required for nuclear translocation of FLOT1. PTOV1 promotes cell proliferation. There are three named isoforms.

Function:
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.

Subunit:
Interacts with PTH1R (via N-terminal extracellular domain).

Subcellular Location:
Secreted.

DISEASE:
Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

Similarity:
Belongs to the parathyroid hormone family.

SWISS:
Q86YD1

Gene ID:
53635

Database links:

 Human

 Mouse

 Rat

 Human

 Cow

 Human

 Mouse

 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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